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Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.

A substance that competes for opiate receptor binding has been isolated from calf brain and identified as two pentapeptides, H-Tyr-Gly-Gly-Phe-Met-OH (methionine enkephalin) and H-Tyr-Gly-Gly-Phe-Leu-OH (leucine enkephalin), with about four times more leucine enkephalin than methionine enkephalin. S...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Simantov, R, Snyder, S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1976
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430630/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1065904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.7.2515
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