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Opportunities and challenges of clinical trials in cardiology using composite primary endpoints

In clinical trials, the primary efficacy endpoint often corresponds to a so-called “composite endpoint”. Composite endpoints combine several events of interest within a single outcome variable. Thereby it is intended to enlarge the expected effect size and thereby increase the power of the study. Ho...

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Bibliografische gegevens
Gepubliceerd in:World J Cardiol
Hoofdauteurs: Rauch, Geraldine, Rauch, Bernhard, Schüler, Svenja, Kieser, Meinhard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Baishideng Publishing Group Inc 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306200/
https://ncbi.nlm.nih.gov/pubmed/25632312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4330/wjc.v7.i1.1
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