Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10

AIM: To investigate the expression of matrix metallopr-oteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic fibrosis and the antifibrogenic role of exogenous interleukin-10 (IL-10). METHODS: Hepatic fibrosis was induced by CCl(4) administration and 60 male Sprague-Dawley rats were rando...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Zheng, Wei-Da, Zhang, Li-Juan, Shi, Mei-Na, Chen, Zhi-Xin, Chen, Yun-Xin, Huang, Yue-Hong, Wang, Xiao-Zhong
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2005
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305868/
https://ncbi.nlm.nih.gov/pubmed/15793858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i12.1753
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