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Effects of interferon-alpha on expression of hepatic stellate cell and transforming growth factor-β1 and α-smooth muscle actin in rats with hepatic fibrosis

AIM: To investigate the effect of interferon-α (IFN-α) on preventing or reversing hepatic fibrosis in rat experimental model induced by CCl(4). METHODS: One hundred and ten Sprague-Dawley rats were divided into five groups: group A (normal controls, n = 18), group B (fibrotic model controls, n = 22)...

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Publicat a:World J Gastroenterol
Autors principals: Chang, Xin-Ming, Chang, Ying, Jia, Ai
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305756/
https://ncbi.nlm.nih.gov/pubmed/15849824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i17.2634
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