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Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II.

Serum contains a polypeptide with insulin-like activity not suppressible by insulin antibodies (NSILA). A large-scale isolation procedure for NSILA is described, starting from an acid ethanol extract of a Cohn fraction (precipitate B) obtained from human plasma. Two homogenous polypeptides with insu...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rinderknecht, E, Humbel, R E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1976
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1065887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.7.2365
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