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Human somatotropin: restoration of full biological activity by noncovalent interaction of a natural and a synthetic fragment of the hormone.

The recombinant hormone obtained by noncovalent interaction of the natural NH2-terminal fragment (consisting of 134 amino acid residues) with a synthetic COOH-terminal fragment of 52 amino acids of the reduced-carbamidomethylated human somatotropin molecule is found to exhibit full biological activi...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Li, C H, Bewley, T A, Blake, J, Hayashida, T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1977
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/265545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.3.1016
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