Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli.

Bacillus circulans NRRL B-3312, a nonpathogenic bacterium that produces the aminoglycoside antibiotic butirosin, is known to contain an aminoglycoside phosphotransferase that is similar to the neomycin phosphotransferases of clinically isolated antibiotic-resistant bacteria. Purified DNAs from B. ci...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Courvalin, P, Weisblum, B, Davies, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1977
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/322154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.3.999
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