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Understanding the Roles of FAK in Cancer: Inhibitors, Genetic Models, and New Insights

Focal adhesion kinase (FAK) is a protein tyrosine kinase that regulates cellular adhesion, motility, proliferation and survival in various types of cells. Interestingly, FAK is activated and/or overexpressed in advanced cancers, and promotes cancer progression and metastasis. For this reason, FAK be...

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書目詳細資料
發表在:J Histochem Cytochem
Main Authors: Yoon, Hyunho, Dehart, Joshua P., Murphy, James M., Lim, Ssang-Taek Steve
格式: Artigo
語言:Inglês
出版: SAGE Publications 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305513/
https://ncbi.nlm.nih.gov/pubmed/25380750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155414561498
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