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GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

The lateral habenula (LHb), a key regulator of monoaminergic brain regions, is activated by negatively-valenced events. Its hyperactivity is associated with depression. While enhanced excitatory input to the LHb has been linked to depression, little is known about inhibitory transmission. We discove...

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Vydáno v:Science
Hlavní autoři: Shabel, Steven J., Proulx, Christophe D., Piriz, Joaquin, Malinow, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305433/
https://ncbi.nlm.nih.gov/pubmed/25237099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1250469
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