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Modelling epidermis homoeostasis and psoriasis pathogenesis

We present a computational model to study the spatio-temporal dynamics of epidermis homoeostasis under normal and pathological conditions. The model consists of a population kinetics model of the central transition pathway of keratinocyte proliferation, differentiation and loss and an agent-based mo...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Zhang, Hong, Hou, Wenhong, Henrot, Laurence, Schnebert, Sylvianne, Dumas, Marc, Heusèle, Catherine, Yang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305409/
https://ncbi.nlm.nih.gov/pubmed/25566881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.1071
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