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Junctional Adhesion Molecule A Promotes Epithelial Tight Junction Assembly to Augment Lung Barrier Function

Epithelial barrier function is maintained by tight junction proteins that control paracellular fluid flux. Among these proteins is junctional adhesion molecule A (JAM-A), an Ig fold transmembrane protein. To assess JAM-A function in the lung, we depleted JAM-A in primary alveolar epithelial cells us...

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Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Mitchell, Leslie A., Ward, Christina, Kwon, Mike, Mitchell, Patrick O., Quintero, David A., Nusrat, Asma, Parkos, Charles A., Koval, Michael
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305184/
https://ncbi.nlm.nih.gov/pubmed/25438062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.10.010
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