Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy

OBJECTIVES: Lupus nephritis (LN) is a major cause of morbidity in patients with systemic lupus erythematosus (SLE). B cells have a central role in the pathogenesis of SLE. B lymphocyte stimulator (BLyS) and a proliferation inducing ligand (APRIL) are pivotal in B cell homeostasis. We aimed to invest...

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Detalhes bibliográficos
Publicado no:Lupus Sci Med
Main Authors: Parodis, Ioannis, Zickert, Agneta, Sundelin, Birgitta, Axelsson, Magnus, Gerhardsson, Jakob, Svenungsson, Elisabet, Malmström, Vivianne, Gunnarsson, Iva
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Lupus Nephritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305068/
https://ncbi.nlm.nih.gov/pubmed/25632350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2014-000061
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