Genetic Analysis of the Pathogenic Molecular Sub-phenotype Interferon Alpha Identifies Multiple Novel Loci Involved in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder characterized by inflammation of multiple organ systems and dysregulated interferon responses. SLE is both genetically and phenotypically heterogeneous, greatly reducing the power of case-control studies in SLE. Elevated circulating...

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Vydáno v:Genes Immun
Hlavní autoři: Kariuki, Silvia N., Ghodke-Puranik, Yogita, Dorschner, Jessica M., Chrabot, Beverly S., Kelly, Jennifer A., Tsao, Betty P., Kimberly, Robert P., Alarcón-Riquelme, Marta E., Jacob, Chaim O., Criswell, Lindsey A., Sivils, Kathy L., Langefeld, Carl D., Harley, John B., Skol, Andrew D., Niewold, Timothy B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305028/
https://ncbi.nlm.nih.gov/pubmed/25338677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.57
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