Targeting CDK11 in osteosarcoma cells using the CRISPR-Cas9 system

Osteosarcoma is the most common type primary malignant tumor of bone. Patients with regional osteosarcoma are routinely treated with surgery and chemotherapy. In addition, many patients with metastatic or recurrent osteosarcoma show poor prognosis with current chemotherapy agents. Therefore, it is i...

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Bibliographic Details
Published in:J Orthop Res
Main Authors: Feng, Yong, Sassi, Slim, Shen, Jacson K, Yang, Xiaoqian, Gao, Yan, Osaka, Eiji, Zhang, Jianming, Yang, Shuhua, Yang, Cao, Mankin, Henry J., Hornicek, Francis J, Duan, Zhenfeng
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304907/
https://ncbi.nlm.nih.gov/pubmed/25348612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22745
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