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Glucocorticoids increase excitotoxic injury and inflammation in the hippocampus of adult male rats

BACKGROUND/AIMS: Stress exacerbates neuron loss in many CNS injuries via the actions of adrenal glucocorticoid (GC) hormones. For some injuries, this GC-endangerment of neurons is accompanied by greater immune cell activation in the CNS, a surprising outcome given the potent immunosuppressive proper...

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Bibliografski detalji
Izdano u:Neuroendocrinology
Glavni autori: Sorrells, Shawn F., Munhoz, Carolina D., Manley, Nathan C., Yen, Sandra, Sapolsky, Robert M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304880/
https://ncbi.nlm.nih.gov/pubmed/25228100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000367849
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