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Estimating the Cost-Effectiveness of Pre-Exposure Prophylaxis to Reduce HIV-1 and HSV-2 Incidence in HIV-Serodiscordant Couples in South Africa

OBJECTIVE: To estimate the cost-effectiveness of daily oral tenofovir-based PrEP, with a protective effect against HSV-2 as well as HIV-1, among HIV-1 serodiscordant couples in South Africa. METHODS: We incorporated HSV-2 acquisition, transmission, and interaction with HIV-1 into a microsimulation m...

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Vydáno v:PLoS One
Hlavní autoři: Jewell, Britta L., Cremin, Ide, Pickles, Michael, Celum, Connie, Baeten, Jared M., Delany-Moretlwe, Sinead, Hallett, Timothy B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304839/
https://ncbi.nlm.nih.gov/pubmed/25616135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115511
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