Genotype and risk of major bleeding during warfarin treatment

AIM: To determine whether genetic variants associated with warfarin dose variability were associated with increased risk of major bleeding during warfarin therapy. MATERIALS & METHODS: Using Vanderbilt’s DNA biobank we compared the prevalence of CYP2C9, VKORC1 and CYP4F2 variants in 250 cases wi...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Kawai, Vivian K, Cunningham, Andrew, Vear, Susan I, Van Driest, Sara L, Oginni, Abimbola, Xu, Hua, Jiang, Min, Li, Chun, Denny, Joshua C, Shaffer, Christian, Bowton, Erica, Gage, Brian F, Ray, Wayne A, Roden, Dan M, Stein, C Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304738/
https://ncbi.nlm.nih.gov/pubmed/25521356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.153
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