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Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells

Id proteins are dominant-negative regulators within the HLH family of proteins. In embryonic stem cells (ESCs), Id1 and Id3 maintain the pluripotent state by preventing neural differentiation. The Id1-interacting protein Zrf1 plays a crucial role as a chromatin-bound factor in specification of the n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO Rep
Hauptverfasser: Aloia, Luigi, Gutierrez, Arantxa, Caballero, Juan Martin, Di Croce, Luciano
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304729/
https://ncbi.nlm.nih.gov/pubmed/25361733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439560
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