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beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.

The hypophysial homomeric peptide beta-lipotropin (beta-LPH-[1-91]) has no morphinomomimetic activity in a bioassay (myenteric plexus-longitudinal muscle of the guinea pig's ileum) or binding assays with stereospecific opiate-receptors of rat brain synaptosome preparations. Incubating beta-LPH-[1-91...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Lazarus, L H, Ling, N, Guillemin, R
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1976
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430469/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1064883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.6.2156
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