Mechanism of human lymphocyte stimulation by concanavalin A: role of valence and surface binding sites.

A monovalent form of concanavalin A (m-Con A) has been prepared to determine the importance of valence for human lymphocyte surface binding and subsequent lymphocyte stimulation as measured by blast transformation and cytotoxicity. Concanavalin A (Con A) was fragmented by a proteolytic process and t...

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Bibliographic Details
Main Authors: Wands, J R, Podolsky, D K, Isselbacher, K J
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC430461/
https://ncbi.nlm.nih.gov/pubmed/1064878
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