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Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake

The efficient delivery of chemotherapeutics to the tumor via nanoparticle (NP)-based delivery systems remains a significant challenge. This is compounded by the fact that the tumor is highly dynamic and complex environment composed of a plurality of cell types and extracellular matrix. Since glycosa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lamichhane, Surya P, Arya, Neha, Ojha, Nirdesh, Kohler, Esther, Shastri, V Prasad
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304601/
https://ncbi.nlm.nih.gov/pubmed/25632234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S73508
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