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Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity
Immune responses must be well restrained in a steady state to avoid excessive inflammation. However, such restraints are quickly removed to exert anti-microbial responses. Here, we report a role of autophagy in an early host anti-fungal response by enhancing NFκB activity through A20 sequestration....
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304414/ https://ncbi.nlm.nih.gov/pubmed/25609235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6779 |
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