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Chromatin De-Compaction By The Nucleosomal Binding Protein HMGN5 Impairs Nuclear Sturdiness

In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the nucleus. We show that in cultured cells, chromatin de-compaction by the nucleosome binding protein HMGN5 decreases the sturdiness, elasticity, a...

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Foilsithe in:Nat Commun
Main Authors: Furusawa, Takashi, Rochman, Mark, Taher, Leila, Dimitriadis, Emilios K., Nagashima, Kunio, Anderson, Stasia, Bustin, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304400/
https://ncbi.nlm.nih.gov/pubmed/25609380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7138
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