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Chromatin De-Compaction By The Nucleosomal Binding Protein HMGN5 Impairs Nuclear Sturdiness

In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the nucleus. We show that in cultured cells, chromatin de-compaction by the nucleosome binding protein HMGN5 decreases the sturdiness, elasticity, a...

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Vydáno v:Nat Commun
Hlavní autoři: Furusawa, Takashi, Rochman, Mark, Taher, Leila, Dimitriadis, Emilios K., Nagashima, Kunio, Anderson, Stasia, Bustin, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304400/
https://ncbi.nlm.nih.gov/pubmed/25609380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7138
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