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Reduced thrombosis in Klkb1(−/−) mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor
The precise mechanism for reduced thrombosis in prekallikrein null mice (Klkb1(−/−)) is unknown. Klkb1(−/−) mice have delayed carotid artery occlusion times on the rose bengal and ferric chloride thrombosis models. Klkb1(−/−) plasmas have long-activated partial thromboplastin times and defective con...
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| Pubblicato in: | Blood |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304115/ https://ncbi.nlm.nih.gov/pubmed/25339356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-550285 |
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