Reduced thrombosis in Klkb1(−/−) mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor

The precise mechanism for reduced thrombosis in prekallikrein null mice (Klkb1(−/−)) is unknown. Klkb1(−/−) mice have delayed carotid artery occlusion times on the rose bengal and ferric chloride thrombosis models. Klkb1(−/−) plasmas have long-activated partial thromboplastin times and defective con...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Stavrou, Evi X., Fang, Chao, Merkulova, Alona, Alhalabi, Omar, Grobe, Nadja, Antoniak, Silvio, Mackman, Nigel, Schmaier, Alvin H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2015
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304115/
https://ncbi.nlm.nih.gov/pubmed/25339356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-550285
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