Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction.

Putrescine, the end-product of ornithine decarboxylase (ODC: L-ornithine carboxylyase, EC; 4.1.1.17) action, induces the synthesis of a protein(s), in L1210, neuroblastoma, and H-35 cells as well as in rat liver, which inhibits ODC activity. Spermidine and spermine, distal products of ODC activity,...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Heller, J S, Fong, W F, Canellakis, E S
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1976
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1064859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.6.1858
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