Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin.
The pituitary peptide beta-lipotropin displays essentially no opoid activity in a preparation of guinea pig ileum or in the opiate receptor binding assay. However, a fragment, beta-lipotropin-(61-91), with the enkephalin sequence (Tyr-Gly-Gly-Phe-Met) at its NH2-terminus, has typical opioid effects...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1976
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1064855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.6.1821 |
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