Tumor genome analysis includes germline genome: Are we ready for surprises?

We sought to describe the spectrum of potential and confirmed germline genomic events incidentally identified during routine medium-throughput somatic tumor DNA sequencing, and to provide a framework for pre- and post-test consent and counseling for patients and families. Targeted tumor-only next-ge...

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Podrobná bibliografie
Vydáno v:Int J Cancer
Hlavní autoři: Catenacci, Daniel VT, Amico, Andrea L, Nielsen, Sarah M, Geynisman, Daniel M, Rambo, Brittany, Carey, George B, Gulden, Cassandra, Fackenthal, Jim, Marsh, Robert D, Kindler, Hedy L, Olopade, Olufunmilayo I
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Cancer Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303936/
https://ncbi.nlm.nih.gov/pubmed/25123297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29128
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