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The Cytolytic Activity of Vaginolysin Strictly Depends on Cholesterol and Is Potentiated by Human CD59

Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dependent cytolysins (CDCs) whose pore-formi...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Principais autores: Zilnyte, Milda, Venclovas, Česlovas, Zvirbliene, Aurelija, Pleckaityte, Milda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303817/
https://ncbi.nlm.nih.gov/pubmed/25590277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7010110
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