Developmental Expression of N-Methyl-d-Aspartate (NMDA) Receptor Subunits in Human White and Gray Matter: Potential Mechanism of Increased Vulnerability in the Immature Brain

The pathophysiology of perinatal brain injury is multifactorial and involves hypoxia-ischemia (HI) and inflammation. N-methyl-d-aspartate receptors (NMDAR) are present on neurons and glia in immature rodents, and NMDAR antagonists are protective in HI models. To enhance clinical translation of roden...

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Publicado en:Cereb Cortex
Autores principales: Jantzie, Lauren L., Talos, Delia M., Jackson, Michele C., Park, Hyun-Kyung, Graham, Dionne A., Lechpammer, Mirna, Folkerth, Rebecca D., Volpe, Joseph J., Jensen, Frances E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303802/
https://ncbi.nlm.nih.gov/pubmed/24046081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bht246
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