Fab fragment glycosylated IgG may play a central role in placental immune evasion

STUDY QUESTION: How does the placenta protect the fetus from immune rejection by the mother? SUMMARY ANSWER: The placenta can produce IgG that is glycosylated at one of its Fab arms (asymmetric IgG; aIgG) which can interact with other antibodies and certain leukocytes to affect local immune reaction...

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Bibliografski detalji
Izdano u:Hum Reprod
Glavni autori: Gu, Jiang, Lei, Yu, Huang, Yuanping, Zhao, Yingying, Li, Jing, Huang, Tao, Zhang, Junjun, Wang, Juping, Deng, Xiaodong, Chen, Zhengshan, Korteweg, Christine, Deng, Ruishu, Yan, Meiling, Xu, Qian, Dong, Shengnan, Cai, Monghong, Luo, Lili, Huang, Guowei, Wang, Yun, Li, Qian, Lin, Changmei, Su, Meng, Yang, Chunzhang, Zhuang, Zhengping
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303772/
https://ncbi.nlm.nih.gov/pubmed/25505012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/deu323
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