Nuclear magnetic resonance study of heme-heme interaction in hemoglobin M Milwaukee: implications concerning the mechanism of cooperative ligand binding in normal hemoglobin.

Hemoglobin M Milwaukee (beta 67E11 val leads to Glu) is a naturally occurring valency hybrid containing two permanently oxidized hemes in the beta-chains. In this mutant, the two abnormal beta-chains cannot combine with oxygen, whereas the two alpha-chains are normal and can combine with oxygen coop...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Fung, L W, Minton, A P, Ho, C
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1976
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1064027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.5.1581
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