Secreted Herpes Simplex Virus-2 Glycoprotein G Modifies NGF-TrkA Signaling to Attract Free Nerve Endings to the Site of Infection

Herpes simplex virus type 1 (HSV-1) and HSV-2 are highly prevalent viruses that cause a variety of diseases, from cold sores to encephalitis. Both viruses establish latency in peripheral neurons but the molecular mechanisms facilitating the infection of neurons are not fully understood. Using surfac...

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Publicat a:PLoS Pathog
Autors principals: Cabrera, Jorge Rubén, Viejo-Borbolla, Abel, Martinez-Martín, Nadia, Blanco, Soledad, Wandosell, Francisco, Alcamí, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303327/
https://ncbi.nlm.nih.gov/pubmed/25611061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004571
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