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SHP-2 Mediates Target-Regulated Axonal Termination and NGF-Dependent Neurite Growth in Sympathetic Neurons

The tyrosine phosphatase SHP-2 has been implicated in a variety of signaling pathways, including those mediated by neurotrophins in neurons. To examine the role of SHP-2 in the development of sympathetic neurons, we inhibited the function of SHP-2 in transgenic mice by overexpressing a catalytically...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Chen, Bo, Hammonds-Odie, Latanya, Perron, Jeanette, Masters, Brian A., Bixby, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303248/
https://ncbi.nlm.nih.gov/pubmed/12482708
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