Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis

INTRODUCTION: Human Epidermal Growth Factor Receptor (ERBB4/HER4) belongs to the Epidermal Growth Factor receptor/ERBB family of receptor tyrosine kinases. While ERBB1, ERBB2 and ERBB3 are often overexpressed or activated in breast cancer, and are oncogenic, the role of ERBB4 in breast cancer is unc...

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Publicat a:Breast Cancer Res
Autors principals: Wali, Vikram B, Gilmore-Hebert, Maureen, Mamillapalli, Ramanaiah, Haskins, Jonathan W, Kurppa, Kari J, Elenius, Klaus, Booth, Carmen J, Stern, David F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303208/
https://ncbi.nlm.nih.gov/pubmed/25516216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0501-z
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