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Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis

INTRODUCTION: Human Epidermal Growth Factor Receptor (ERBB4/HER4) belongs to the Epidermal Growth Factor receptor/ERBB family of receptor tyrosine kinases. While ERBB1, ERBB2 and ERBB3 are often overexpressed or activated in breast cancer, and are oncogenic, the role of ERBB4 in breast cancer is unc...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Wali, Vikram B, Gilmore-Hebert, Maureen, Mamillapalli, Ramanaiah, Haskins, Jonathan W, Kurppa, Kari J, Elenius, Klaus, Booth, Carmen J, Stern, David F
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303208/
https://ncbi.nlm.nih.gov/pubmed/25516216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0501-z
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