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The small molecule C-6 is selectively cytotoxic against breast cancer cells and its biological action is characterized by mitochondrial defects and endoplasmic reticulum stress

INTRODUCTION: The establishment of drug resistance following treatment with chemotherapeutics is strongly associated with poor clinical outcome in patients, and drugs that target chemoresistant tumors have the potential to increase patient survival. In an effort to identify biological pathways of ch...

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Publicado no:Breast Cancer Res
Main Authors: Vaden, Rachel M, Gligorich, Keith M, Jana, Ranjan, Sigman, Matthew S, Welm, Bryan E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303206/
https://ncbi.nlm.nih.gov/pubmed/25425314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0472-0
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