HLA-B allele and haplotype diversity among Thai patients identified by PCR-SSOP: evidence for high risk of drug-induced hypersensitivity

Background: There are 3 classes of HLA molecules; HLA class I, II and III, of which different classes have different functions. HLA-B gene which belongs to HLA class I play an important role predicting drug hypersensitivity. Materials and Methods: Nine hundred and eighty-six Thai subjects who regist...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Puangpetch, Apichaya, Koomdee, Napatrupron, Chamnanphol, Montri, Jantararoungtong, Thawinee, Santon, Siwalee, Prommas, Santirhat, Hongkaew, Yaowaluck, Sukasem, Chonlaphat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302987/
https://ncbi.nlm.nih.gov/pubmed/25657656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00478
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