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Analysis of Primate Genomic Variation Reveals a Repeat-Driven Expansion of the Human Genome

We performed a detailed analysis of both single-nucleotide and large insertion/deletion events based on large-scale comparison of 10.6 Mb of genomic sequence from lemur, baboon, and chimpanzee to human. Using a human genomic reference, optimal global alignments were constructed from large (>50-kb) g...

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Udgivet i:Genome Res
Principais autores: Liu, Ge, Program, NISC Comparative Sequencing, Zhao, Shaying, Bailey, Jeffrey A., Sahinalp, S. Cenk, Alkan, Can, Tuzun, Eray, Green, Eric D., Eichler, Evan E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2003
Fag:
Letters
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12618366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.923303
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