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The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells

The transcription factor p63 (Trp63) plays a key role in homeostasis and regeneration of the skin. The p63 gene is transcribed from dual promoters, generating TAp63 isoforms with growth suppressive functions and dominant-negative ΔNp63 isoforms with opposing properties. p63 also encodes multiple car...

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Vydáno v:Development
Hlavní autoři: Suzuki, Daisuke, Sahu, Raju, Leu, N. Adrian, Senoo, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302837/
https://ncbi.nlm.nih.gov/pubmed/25503409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.118307
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