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SLAM: Cross-Species Gene Finding and Alignment with a Generalized Pair Hidden Markov Model
Comparative-based gene recognition is driven by the principle that conserved regions between related organisms are more likely than divergent regions to be coding. We describe a probabilistic framework for gene structure and alignment that can be used to simultaneously find both the gene structure a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC430255/ https://ncbi.nlm.nih.gov/pubmed/12618381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.424203 |
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