Quantification of Peptides from Immunoglobulin Constant and Variable Regions by Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry for Assessment of Multiple Myeloma Patients

PURPOSE: Quantitative mass spectrometry assays for immunoglobulins (Igs) are compared with existing clinical methods in samples from patients with plasma cell dyscrasias, e.g. multiple myeloma. EXPERIMENTAL DESIGN: Using LC-MS/MS data, Ig constant region peptides and transitions were selected for li...

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Veröffentlicht in:Proteomics Clin Appl
Hauptverfasser: Remily-Wood, Elizabeth R., Benson, Kaaron, Baz, Rachid C., Chen, Y. Ann, Hussein, Mohamad, Hartley-Brown, Monique A., Sprung, Robert W., Perez, Brianna, Liu, Richard Z., Yoder, Sean, Teer, Jamie, Eschrich, Steven A., Koomen, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302417/
https://ncbi.nlm.nih.gov/pubmed/24723328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201300077
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