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Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia

OBJECTIVES: Aberrant DNA methylation and gene expression have been reported in postmortem brain tissues of psychotic patients, but until now there has been no systematic evaluation of synergistic changes in methylation and expression on a genome-wide scale from brain tissue. METHODS: In this study,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bipolar Disord
Hauptverfasser: Chen, Chao, Zhang, Chunling, Cheng, Lijun, Reilly, James L, Bishop, Jeffrey R, Sweeney, John A, Chen, Hua-yun, Gershon, Elliot S, Liu, Chunyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302408/
https://ncbi.nlm.nih.gov/pubmed/25243493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12255
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