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Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases.

The parenteral administration of a single dose of 3-methylcholanthrene to rats caused an increase in the liver of the concentration of 3', 5'-cAMP and of the activity of cAMP-dependent protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37). These events were followed by an increased activity o...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Byus, C V, Costa, M, Sipes, I G, Brodie, B B, Russell, D H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/177981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.4.1241
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