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Dephosphorylation of nonhistone proteins specifically alters the pattern of gene transcription in reconstituted chromatin.

A nonhistone phosphatase devoid of detectable protease activity has been purified from nuclear sap by chromatography on DEAE-Sephadex. After linkage to an insoluble agarose matrix, this enzyme was used to dephosphorylate nonhistone proteins obtained from S-phase HeLa cells. Chromatin reconstituted w...

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Detalhes bibliográficos
Main Authors: Kleinsmith, L J, Stein, J, Stein, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430223/
https://ncbi.nlm.nih.gov/pubmed/177978
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