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An altered apurinic DNA endonuclease activity in group A and group D xeroderma pigmentosum fibroblasts.

Endonuclease activity upon depurinated DNA was measured in extracts of cultured fibroblasts from xeroderma pigmentosum patients. Cell lines from complementation groups A, B, C, E, and the XP-variant had slightly reduced levels of activity, but cell lines from complementation group D had one-sixth of...

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Detalhes bibliográficos
Main Authors: Kuhnlein, U, Penhoet, E E, Linn, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430222/
https://ncbi.nlm.nih.gov/pubmed/1063398
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