Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.

Eukaryotic cells require N-linked carbohydrates for survival. However, the biosynthetic intermediate Man5GlcNAc2Asn, in place of mature N-linked structures, allows glycoprotein synthesis and somatic cell growth to proceed normally. To determine whether the same would be true in a complex biological...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Ioffe, E, Stanley, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43022/
https://ncbi.nlm.nih.gov/pubmed/8290590
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items