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A TAK1 Signaling Pathway Critically Regulates Myocardial Survival and Remodeling

BACKGROUND: Programmed necrosis (necroptosis) plays an important role in development, tissue homeostasis, and disease pathogenesis. The molecular mechanisms that regulate necroptosis in the heart and its physiological relevance in myocardial remodeling and heart failure remain largely unknown. METHO...

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Bibliografische gegevens
Gepubliceerd in:Circulation
Hoofdauteurs: Li, Lei, Chen, Yi, Doan, Jessica, Murray, Jason, Molkentin, Jeffery D., Liu, Qinghang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302054/
https://ncbi.nlm.nih.gov/pubmed/25278099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.011195
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