Pooled PCR testing strategy and prevalence estimation of submicroscopic infections using Bayesian latent class models in pregnant women receiving intermittent preventive treatment at Machinga District Hospital, Malawi, 2010

BACKGROUND: Low malaria parasite densities in pregnancy are a diagnostic challenge. PCR provides high sensitivity and specificity in detecting low density of parasites, but cost and technical requirements limit its application in resources-limited settings. Pooling samples for PCR detection was expl...

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Udgivet i:Malar J
Main Authors: Zhou, Zhiyong, Mitchell, Rebecca Mans, Gutman, Julie, Wiegand, Ryan E, Mwandama, Dyson A, Mathanga, Don P, Skarbinski, Jacek, Shi, Ya Ping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301903/
https://ncbi.nlm.nih.gov/pubmed/25522751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-509
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