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Biological activity of catecholamines covalently linked to synthetic polymers: proof of immobilized drug theory.

l-Isoproterenol was covalently coupled via an azo linkage to soluble copolypeptides of molecular weight 1500 and 10,000 containing an aromatic amine. The polymeric azo-isoproterenol derivatives were purified by gel chromatography which reduced contamination by the parent isoproterenol to undetectabl...

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Autors principals: Verlander, M S, Venter, J C, Goodman, M, Kaplan, N O, Saks, B
Format: Artigo
Idioma:Inglês
Publicat: 1976
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC430189/
https://ncbi.nlm.nih.gov/pubmed/1063386
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