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Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3 expression in a transcript-specific manner

BACKGROUND: The ZFHX3 gene, located in Chromosome 16q22.3, codes for a transcription factor which is widely expressed in human tissues. Genome-wide studies have identified associations between variants within the gene and Kawasaki disease and atrial fibrillation. ZFHX3 has two main transcripts that...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Martin, Ruairidh I R, Owens, W Andrew, Cunnington, Michael S, Mayosi, Bongani M, Koref, Mauro Santibáñez, Keavney, Bernard D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301889/
https://ncbi.nlm.nih.gov/pubmed/25539802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-014-0136-1
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